Veterinary advice, Dog, Cat

Chronic Kidney Disease (CKD) is a subtle disease, not always easy to diagnose, because often when the symptoms are evident, they are already an indication of advanced disease. For this reason, annual screening is recommended for pets over 7-8 years of age.

This disease consists of a slow degeneration of kidney function (excretory and endocrine function), in particular of the nephrons: these functional units of the kidney deputed to purification (and not only) are first subjected to an inflammatory process, and then more or less gradually lose their function completely and are replaced by scar tissue.

Fortunately, however, the kidney has an exceptional ability to compensate; it can therefore continue to function for a long time without any noticeable symptoms.

Kidney failure in general can be of two types:

  • Acute, i.e. with sudden onset, which can be caused by trauma, intoxication. Usually, this type of failure can be fatal if it is not diagnosed and managed quickly.
  • Chronic, i.e. slower onset, can last for months or even years, leading to a masking of symptoms as the kidney gradually compensates for the loss of function. Typically, more than 75% of the nephrons are affected.

The causes of chronic kidney failure can be infectious diseases, neoplasms, inflammatory states, but also urinary stones and urinary obstructions (these causes are very common in cats).

The symptoms of chronic kidney failure are not so obvious right away. Usually, dogs and cats start to show increased thirst and increased urine output. These two symptoms are rather general and can also be attributable to other diseases such as diabetes. As the disease progresses, more important symptoms such as lack of appetite, vomiting, dehydration, ulcers and weight loss occur. All these are indicative of a state of intoxication in the cat due to kidney malfunction and the accumulation of substances in the blood such as nitrogen and urea.

There are four stages of kidney failure, depending on the severity of the pathology and the values of certain substances that are examined, including Azotemia, Creatinine and Proteinuria. Depending on the stage in which our dog or cat finds itself, it is possible to institute a type of therapy which, however, must be clear, will never lead to a complete cure, but rather to a better management of the patient, to reduce the progression of the disease, reduce the symptoms due to intoxication and give less workload to the kidney. The use of specific foods containing high quality, highly digestible protein and a low content of phosphorus and other minerals helps our four-legged friends not to overload their kidneys. In addition, there is increasing interest in the development of kidney supplements, often made from naturally occurring substances, which support the purification function of the kidney and alleviate certain symptoms, thus improving the quality of life of dogs and cats suffering from this disease. Recently, it has also been shown that mushrooms from traditional Chinese medicine such as Cordyceps and Reishi can be an excellent support for medical therapy.

Remember that early diagnosis of this disease is essential in order to be able to start supportive therapy from the earliest symptoms or even the first signs of kidney malfunction. This is why it is important to take your dog or cat for a check-up, especially when they reach a certain age, to assess whether any changes are already present with a simple blood test.

Always take care of their diet from a young age and visit your vet regularly - they will be grateful to you for the rest of their lives.

270060393 1609096832785498 6174521712134765943 n
It might also interest you

For the lucky ones, June is already holiday time or, at any rate, the possibility of taking short trips increases. Sea, mountain, lake or city of art, the choice of destination is wide but are we really ready to enjoy these experiences together with our inseparable friends?


How many of you have had to convince and drag your dogs to the vet because they point their paws as soon as they see where you are going? And what about all kinds of strategies to get your cats into the carrier?


The cat is now known to be a very sensitive and susceptible animal. Its territorial nature means that it carefully classifies the spaces at its disposal, dividing them into areas dedicated to activity (such as feeding, playing, hunting or eliminating) and isolation, where it can rest (usually in high areas where it has control of the environment around it).


You often see photos of overweight cats and dogs, which look a bit funny because of the positions they assume for their weight, but if you look closely at this problem, there is probably little to smile about.

Subscribe to the newsletter